1. Signaling Pathways
  2. Apoptosis
  3. RIP kinase
  4. RIP kinase Inhibitors

RIP kinase Inhibitors

RIPK1

RIPK2

RIPK3

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

RIP kinase Inhibitors & Activators
Product Name RIPK1 RIPK2 RIPK3 Purity
GSK-872    
RIPK3
99.91%
Necrostatin 2 racemate
RIPK1
    99.65%
UH15-38    
RIPK3, IC50: 20 nM
99.80%
RIPK1-IN-25
RIPK1, EC50: 19.9 nM
RIPK1, Kd: 25 nM
   
GSK-872 hydrochloride    
RIPK3
99.21%
GSK-843    
RIPK3
99.18%
Apostatin-1
RIPK1
    99.24%
WEHI-345  
RIPK2
  99.31%
GSK2983559  
RIPK2
  98.82%
ICCB-19 hydrochloride
RIPK1
    99.24%
PROTAC RIPK degrader-2  
RIPK2
  99.48%
OD36  
RIPK2, IC50: 5.3 nM
  98.70%
RIPK3-IN-1    
RIPK3, IC50: 9.1 nM
99.19%
GSK2983559 active metabolite  
RIPK2
  98.81%
PK68
RIPK1, IC50: 90 nM
RIPK1, EC50: 23 nM
    99.92%
Necrostatin-5
RIPK1
    98.43%
Necrostatin-34
RIPK1
    98.90%
NecroIr1
RIPK1
 
RIPK3
98.02%
RIPK1-IN-4
RIPK1
    98.89%
GSK2983559 free acid  
RIPK2
  99.90%
WEHI-345 analog  
RIPK2
  98.41%
KWCN-41
RIPK1, IC50: 88 nM
    99.83%
NecroIr2
RIPK1
 
RIPK3
98.99%
cRIPGBM chloride  
RIPK2
  99.73%
SZM679
RIPK1, Kd: 8.6 nM
 
RIPK3, Kd: >5000 nM
99.59%
cRIPGBM  
RIPK2
 
RIPK1-IN-18
RIPK1
   
RIP1 kinase inhibitor 7
hRIP1, IC50: <100 nM μM
   
RIPK1-IN-14
RIPK1
   
SZM-1209
RIPK1, Kd: 85 nM
 
RIPK3, Kd: >10000 nM
RIPK1-IN-22
RIPK1
   
NDs-IN-1
RIPK1
   
RIPK1-IN-19
RIPK1, IC50: 15 nM
    ≥98.0%
OD36 hydrochloride  
RIPK2, IC50: 5.3 nM
 
RIPK2-IN-2  
RIPK2
 
RIPK1-IN-23
RIPK1
   
Nec-3a
RIPK1, IC50: 0.44 μM
   
RIP1 kinase inhibitor 4
RIPK1, EC50: ≤ 1000 nM nM
   
Ocadusertib
RIPK1
   
RIP2 Kinase Inhibitor 4  
RIPK2, pIC50: 8
 
Necroptosis-IN-5
RIPK1